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Updated: Wed, 01 May 2013 15:15:00 GMT | By Felicity Thistlethwaite & Colleen Last
Lady Gaga and Perez Hilton: When celebrity friendships end

Jake Gyllenhaal Ryan Phillippe

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These former work-out buddies famously fell out after Donnie Darko actor Jake began dating Ryan’s ex-wife Reese Witherspoon.