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Updated: Wed, 01 May 2013 15:15:00 GMT | By Felicity Thistlethwaite & Colleen Last
Lady Gaga and Perez Hilton: When celebrity friendships end

Courteney Cox and Jennifer Aniston

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Courteney Cox and Jennifer Aniston's was one of the strongest friendships in Hollywood, but the actresses haven’t been photographed together in over two years. The former best friends both attended the same showbiz event in Hollywood recently, but were snapped separately.

The pair drifted apart when Jennifer started seeing Justin Theroux. Then when Courteney’s marriage to David Arquette fell apart, her old Friends co-star was nowhere to be seen.